A Missouri native, Dr. David Crane earned his medical degree from the University of Missouri School of Medicine in 1995. After completing his residency in emergency medicine at Maricopa Medical Center in Phoenix, Arizona, he pursued a dual fellowship program in emergency medicine and primary care sports medicine at Allegheny General Hospital (Duquesne University) in Pittsburgh, Pennsylvania.

After completing his advanced fellowship training, Dr. Crane returned to Missouri in 2000, where he was a staff physician at Barnes Jewish Hospital and St. John’s Mercy Medical Center. In 2005 he started his own practice, Crane Clinic Sports Medicine, and began focusing on regenerative therapies in orthopedics. Dr. Crane subsequently founded Blue Tail Regenerative Therapeutics in 2008, when he began utilizing stem cell grafts with ultrasound guidance.