Dr. Pagnani specializes in sports medicine and surgery of the knee and shoulder. He acted as Head Team Physician for the Nashville Predators NHL Hockey Team from 1998-2007. In addition, he is a consultant to the Miami Dolphins Football Team. Dr. Pagnani has cared for many well-known athletes. He has served as a team physician for the New York Giants, Nashville Kats, Nashville Sounds, Tennessee State University, and several Nashville area high schools. He has also acted as the Team Physician for Elite Runners for Country Music Marathon.

He completed a residency in orthopaedic surgery at the internationally renowned Hospital for Special Surgery in New York City. He also completed a fellowship in sports medicine and shoulder surgery at the Hospital for Special Surgery. Dr. Pagnani was active in high school and collegiate athletics, and has first-hand experience with athletic injuries. A native of Lexington, Kentucky, he made the Kentucky All-State Football Team in high school.